Effects of Growth Hormone on Leptin Gene Expression in Rats
نویسندگان
چکیده
منابع مشابه
Effects of growth hormone on leptin gene expression in rats.
RECENTLY the obesity gene was identified and its gene product, leptin, has demonstrated [1]. It is expressed exclusively in adipocytes, secreted into the blood stream and appears to signal to the hypothalamus through its specific receptor. It reduces appetite and stimulates energy expenditure. Thus it serves an endocrine function in body weight regulation of energy consumption and storage. Sinc...
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Growth hormone (GH) is known to interact with adipose tissue and to induce lipolysis. Adipocytes produce leptin which regulates appetite and energy expenditure. In order to elucidate the role of GH in leptin production, we studied the effect of GH on leptin gene expression and body fat in fatty Zucker rats, a model of obesity with resistance to both leptin and insulin. Recombinant human GH admi...
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background: the hormones of hypothalamo-pituitary-gonadal (hpg) axis have facilitative effects on reproductive behavior in mammals. ghrelin as a starvation hormone has an inhibitory effect on hpg axis’ function. hence, it is postulated that ghrelin may reduce the sexual behavior through inhibiting of hpg axis. the aim of this study was to examine the effects of ghrelin and its antagonist, [d-ly...
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Objective(s): to investigate the chronopharmacological effects of growth hormone on executive function and the oxidative stress response in rats. Materials and Methods: Fifty male Wistar rats (36-40 weeks old) had ad libitum access to water and food and were separated into four groups: diurnal control, nocturnal control, diurnal GH-treated, and nocturnal GH-treated animals. Levels of Cu, Zn sup...
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ژورنال
عنوان ژورنال: Endocrine Journal
سال: 1998
ISSN: 0918-8959,1348-4540
DOI: 10.1507/endocrj.45.suppl_s117